Shalev Gihaz
Company: Yale School of Medicine
Job title: Postdoctoral Researcher
Seminars:
Targeting Pantothenate Kinase as an Effective Strategy for Antifungal Drug Development 10:25 am
Pantothenate kinase (PanK) activity is the first step in Co-enzyme A (CoA) biosynthesis. In fungi, a single PanK gene, CAB1, encodes this function A high-throughput chemical screen identified fungal PanK inhibitors and the CAB1 3D structure revealed essential residues for catalysis, inhibitor binding, and future SAR studies The fungal PanK were validated as targets for…Read more
day: Day Two