Scott Foster
Company: Genentech Inc
Job title: Principal Scientist
Seminars:
[VIRTUAL] Degradation Is Not Always Superior to Enzymatic Inhibition: Lessons Learned from EGFR Heterobifunctional Degraders 4:00 pm
Targeted degradation of EGFR failed to suppress resistance common to EGFR targeted therapies Degradation resulted in decreased efficacy relative to non-degrader controls Comparing degrader vs non-degrader controls highlighted an unexpected role for ER stress contributing to the efficacy of canonical EGFR targeted therapiesRead more
day: Day One