Raghu Kalluri

Raghu Kalluri

Company: University Texas MD Anderson Center

Job title: Professor- Cancer Biology


Targeting Oncogenic KRAS-G12D Mutation Employing Engineered Exosomes in Pancreatic Cancer 11:30 am

Direct inhibitors do not exist for KRAS-G12D We engineered exosomes to deliver siRNA specific to Kras-G12D (iExosomes). The iExosomes target pancreatic cancer cells to suppress tumor growth and increase the overall survival of mice with PDAC Preclinical studies, GLP-toxicology studies, clinical grade GMP production and FDA IND filing led to a Phase I clinical trial…Read more

day: Day Two

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