[VIRTUAL] Sourcing the Immune System to Induce Immunogenic Cell Death In Kras-Colorectal Cancer Cells
Time: 9:30 am
day: Day Two
Details:
- Review how current approaches aimed at inducing immunogenic cell death (ICD) to incite an immune response against cancer neoantigens are based on the use of chemotherapeutics and other agents
- Results are hampered by issues of efficacy, combinatorial approaches, dosing and toxicity. Here, we adopted a strategy based on the use of an immunomolecule that overcomes pharmachemical limitations.
- Cytofluorometry, electron microscopy, RT-PCR, western blotting, apotome immunofluorescence, MLR and xenografts