Markus Queisser

Markus Queisser

Company: GlaxoSmithKline

Job title: Scientific Director

Seminars:

Utilizing PROTACs to Degrade Kinases with Increased Selectivity, Improved Efficacy or PK/PD Disconnect Using Multiple Examples 1:00 pm

Highlighting the advantages of using a degrader vs. catalytic site inhibitors and determining high specificity to minimize off-target effects Optimizing the linkers and E3 ligand for maximal binding, optimize residency time and improving the durability of kinase inhibitor therapeutics Discovering and characterizing a highly cooperative FAK-GSK215-VHL ternary complexRead more

day: Day One

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